Tuesday 22 December 2009

Potassio Canrenoato Pensa




Potassio Canrenoato Pensa may be available in the countries listed below.


Ingredient matches for Potassio Canrenoato Pensa



Potassium Canrenoate

Potassium Canrenoate is reported as an ingredient of Potassio Canrenoato Pensa in the following countries:


  • Italy

International Drug Name Search

Saturday 12 December 2009

Vabadin




Vabadin may be available in the countries listed below.


Ingredient matches for Vabadin



Simvastatin

Simvastatin is reported as an ingredient of Vabadin in the following countries:


  • Poland

  • Slovakia

International Drug Name Search

Thursday 10 December 2009

Dimethicone Spray


Pronunciation: dye-METH-i-kone
Generic Name: Dimethicone
Brand Name: Little Bottoms Daily Care Spray


Dimethicone Spray is used for:

Temporarily protecting and relieving minor skin irritations (eg, diaper rash). It also helps to seal out wetness. It may also be used for other conditions as determined by the patient's doctor.


This product is a skin protectant. It works by relieving skin irritation and reducing redness.


Do NOT use Dimethicone Spray if:


  • the patient is allergic to any ingredient in Dimethicone Spray

Contact your doctor or health care provider right away if this applies to the patient.



Before using Dimethicone Spray:


Tell the patient's health care provider if the patient has any medical conditions, especially if any of the following apply:


  • if the patient is pregnant, planning to become pregnant, or is breast-feeding

  • if the patient is taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if the patient has allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Dimethicone Spray. However, no specific interactions with Dimethicone Spray are known at this time.


Ask the patient's health care provider if Dimethicone Spray may interact with other medicines that the patient takes. Check with the patient's health care provider before the patients starts, stops, or changes the dose of any medicine.


How to use Dimethicone Spray:


Use Dimethicone Spray as directed by the patient's doctor. Check the label on the medicine for exact dosing instructions.


  • Cleanse the diaper area and gently pat dry.

  • Spray Dimethicone Spray onto the affected area as directed by the patient's doctor or on the package label.

  • Wash your hands immediately after using Dimethicone Spray.

  • Apply during each diaper change, especially at bedtime or any time that exposure to a wet diaper may be prolonged.

  • If you miss a dose of Dimethicone Spray, use it as soon as you remember. Continue to use it as directed by the patient's doctor or on the package label.

Ask the patient's health care provider any questions you may have about how to use Dimethicone Spray.



Important safety information:


  • Dimethicone Spray is for external use only. Do not get it in the eyes, nose, or mouth. If you get it in any of these areas, rinse right away with cool water.

  • Do not use Dimethicone Spray on animal bites, deep wounds, infections, lacerations, or serious burns.

  • If symptoms do not get better within 7 days, if they get worse, or if they clear up and then come back, check with the patient's doctor.

  • Talk with the patient's doctor before you use any other medicines on the treated area.

  • PREGNANCY and BREAST-FEEDING: If the patient becomes pregnant, contact her doctor. You will need to discuss the benefits and risks of using Dimethicone Spray while the patient is pregnant. It is not known if Dimethicone Spray is found in breast milk. If the patient is or will be breast-feeding while she uses Dimethicone Spray, check with her doctor. Discuss any possible risks to her baby.


Possible side effects of Dimethicone Spray:


All medicines may cause side effects, but many people have no, or minor side effects. No COMMON side effects have been reported with Dimethicone Spray. Seek medical attention right away if any of these SEVERE side effects occur:



Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); new or worsening skin irritation.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact the patient's health care provider. Call the patient's doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.



If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Dimethicone Spray may be harmful if swallowed.


Proper storage of Dimethicone Spray:

Store Dimethicone Spray at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Do not freeze. Keep Dimethicone Spray out of the reach of children and away from pets.


General information:


  • If you have any questions about Dimethicone Spray, please talk with the patient's doctor, pharmacist, or other health care provider.

  • Dimethicone Spray is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If the patient's symptoms do not improve or if they become worse, check with the patient's doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Dimethicone Spray. If you have questions about the medicine the patient is taking or would like more information, check with the patient's doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Dimethicone resources


  • Dimethicone Use in Pregnancy & Breastfeeding
  • Dimethicone Support Group
  • 8 Reviews for Dimethicone - Add your own review/rating


Compare Dimethicone with other medications


  • Dry Skin

Sunday 6 December 2009

Aristocal




Aristocal may be available in the countries listed below.


Ingredient matches for Aristocal



Calcium Carbonate

Calcium Carbonate is reported as an ingredient of Aristocal in the following countries:


  • Bangladesh

International Drug Name Search

Friday 4 December 2009

Primary Immunodeficiency Syndrome Medications


Drugs associated with Primary Immunodeficiency Syndrome

The following drugs and medications are in some way related to, or used in the treatment of Primary Immunodeficiency Syndrome. This service should be used as a supplement to, and NOT a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.





Drug List:

Wednesday 2 December 2009

Betabioptal




Betabioptal may be available in the countries listed below.


Ingredient matches for Betabioptal



Betamethasone

Betamethasone is reported as an ingredient of Betabioptal in the following countries:


  • Italy

Betamethasone 21-(disodium phosphate) (a derivative of Betamethasone) is reported as an ingredient of Betabioptal in the following countries:


  • Italy

Chloramphenicol

Chloramphenicol is reported as an ingredient of Betabioptal in the following countries:


  • Italy

International Drug Name Search

Ondansetron Alternova




Ondansetron Alternova may be available in the countries listed below.


Ingredient matches for Ondansetron Alternova



Ondansetron

Ondansetron hydrochloride dihydrate (a derivative of Ondansetron) is reported as an ingredient of Ondansetron Alternova in the following countries:


  • Austria

  • Denmark

  • Sweden

International Drug Name Search

Thursday 26 November 2009

Cafergot




In the US, Cafergot (caffeine/ergotamine systemic) is a member of the drug class antimigraine agents and is used to treat Cluster Headaches and Migraine.

US matches:

  • Cafergot

  • Cafergot Suppositories

  • Cafergot oral/rectal

UK matches:

  • Cafergot Suppositories
  • Cafergot Tablets
  • Cafergot Suppositories 2mg (SPC)
  • Cafergot Tablets (SPC)

Ingredient matches for Cafergot



Caffeine

Caffeine is reported as an ingredient of Cafergot in the following countries:


  • Australia

  • Belgium

  • Canada

  • Germany

  • Greece

  • Indonesia

  • Italy

  • Japan

  • New Zealand

  • Oman

  • Spain

  • Switzerland

  • United Kingdom

Ergotamine

Ergotamine tartrate (a derivative of Ergotamine) is reported as an ingredient of Cafergot in the following countries:


  • Australia

  • Bahrain

  • Belgium

  • Canada

  • Germany

  • Greece

  • Indonesia

  • Italy

  • Japan

  • Luxembourg

  • New Zealand

  • Oman

  • Spain

  • Switzerland

  • United Kingdom

International Drug Name Search

Glossary

SPC Summary of Product Characteristics (UK)

Click for further information on drug naming conventions and International Nonproprietary Names.

Wednesday 25 November 2009

C-Tri




C-Tri may be available in the countries listed below.


Ingredient matches for C-Tri



Ceftriaxone

Ceftriaxone is reported as an ingredient of C-Tri in the following countries:


  • Myanmar

International Drug Name Search

Sunday 22 November 2009

Cesarean Section Medications


Definition of Cesarean Section: A surgical procedure that involves the delivery of the foetus through an abdominal incision. C-sections account for about 1/5 of all births in the us. Indications include: failure to progress, foetal distress, cephalopelvic disproportion More...

Drugs associated with Cesarean Section

The following drugs and medications are in some way related to, or used in the treatment of Cesarean Section. This service should be used as a supplement to, and NOT a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

Learn more about Cesarean Section





Drug List:

Monday 16 November 2009

Fluoxetin Medochemie




Fluoxetin Medochemie may be available in the countries listed below.


Ingredient matches for Fluoxetin Medochemie



Fluoxetine

Fluoxetine is reported as an ingredient of Fluoxetin Medochemie in the following countries:


  • Estonia

International Drug Name Search

Friday 13 November 2009

Bonoteo




Bonoteo may be available in the countries listed below.


Ingredient matches for Bonoteo



Minodronic Acid

Minodronic Acid is reported as an ingredient of Bonoteo in the following countries:


  • Japan

International Drug Name Search

Tuesday 10 November 2009

Panthenol-Creme LAW




Panthenol-Creme LAW may be available in the countries listed below.


Ingredient matches for Panthenol-Creme LAW



Dexpanthenol

Dexpanthenol is reported as an ingredient of Panthenol-Creme LAW in the following countries:


  • Germany

International Drug Name Search

Citeral




Citeral may be available in the countries listed below.


Ingredient matches for Citeral



Ciprofloxacin

Ciprofloxacin is reported as an ingredient of Citeral in the following countries:


  • Croatia (Hrvatska)

  • Serbia

Ciprofloxacin hydrochloride (a derivative of Ciprofloxacin) is reported as an ingredient of Citeral in the following countries:


  • Bosnia & Herzegowina

  • Bulgaria

International Drug Name Search

Monday 9 November 2009

Brainolin




Brainolin may be available in the countries listed below.


Ingredient matches for Brainolin



Citicoline

Citicoline is reported as an ingredient of Brainolin in the following countries:


  • Indonesia

International Drug Name Search

Thursday 5 November 2009

Azuleone




Azuleone may be available in the countries listed below.


Ingredient matches for Azuleone



Sodium Gualenate

Sodium Gualenate is reported as an ingredient of Azuleone in the following countries:


  • Japan

International Drug Name Search

Saturday 24 October 2009

Osagren




Osagren may be available in the countries listed below.


Ingredient matches for Osagren



Ozagrel

Ozagrel sodium (a derivative of Ozagrel) is reported as an ingredient of Osagren in the following countries:


  • Japan

International Drug Name Search

Sunday 11 October 2009

Povanyl




Povanyl may be available in the countries listed below.


Ingredient matches for Povanyl



Pyrvinium

Pyrvinium Pamoate is reported as an ingredient of Povanyl in the following countries:


  • France

International Drug Name Search

Saturday 3 October 2009

Harnal D




Harnal D may be available in the countries listed below.


Ingredient matches for Harnal D



Tamsulosin

Tamsulosin hydrochloride (a derivative of Tamsulosin) is reported as an ingredient of Harnal D in the following countries:


  • Indonesia

  • Japan

International Drug Name Search

Thursday 1 October 2009

Nafloxin




Nafloxin may be available in the countries listed below.


Ingredient matches for Nafloxin



Ciprofloxacin

Ciprofloxacin hydrochloride (a derivative of Ciprofloxacin) is reported as an ingredient of Nafloxin in the following countries:


  • Greece

Ciprofloxacin lactate (a derivative of Ciprofloxacin) is reported as an ingredient of Nafloxin in the following countries:


  • Greece

International Drug Name Search

Sunday 27 September 2009

Differin Cream


Pronunciation: a-DAP-a-leen
Generic Name: Adapalene
Brand Name: Differin


Differin Cream is used for:

Treating severe acne. It may also be used for other conditions as determined by your doctor.


Differin Cream is a retinoid-like compound. The exact way Differin Cream works is unknown. However, it helps the skin cells renew quicker and decreases blackhead formation.


Do NOT use Differin Cream if:


  • you are allergic to any ingredient in Differin Cream

Contact your doctor or health care provider right away if any of these apply to you.



Before using Differin Cream:


Some medical conditions may interact with Differin Cream. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have eczema or sunburn

Some MEDICINES MAY INTERACT with Differin Cream. Because little, if any, of Differin Cream is absorbed into the blood, the risk of it interacting with another medicine is low.


Ask your health care provider if Differin Cream may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Differin Cream:


Use Differin Cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • An extra patient leaflet is available with Differin Cream. Talk to your pharmacist if you have questions about this information.

  • Do not use other medicines on your skin without first discussing it with your doctor.

  • Differin Cream is for external use only. Avoid contact with the eyes, lips, angles of the nose, and mucous membranes. Exposure of Differin Cream to the eye may cause swelling, redness, and irritation.

  • Do not apply Differin Cream to cuts, abrasions, eczematous skin, or sunburned skin.

  • Use Differin Cream in the evening before bedtime unless directed otherwise by your doctor.

  • Before applying Differin Cream, clean the area to be treated with mild soap or soapless cleanser and gently dry.

  • Apply a thin film of Differin Cream to the affected and surrounding area. Rub in gently. Wash your hands immediately after using Differin Cream.

  • A mild sensation of warmth or slight stinging may occur shortly after using Differin Cream.

  • If you miss a dose of Differin Cream, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once. If several applications are missed, contact your doctor or pharmacist.

Ask your health care provider any questions you may have about how to use Differin Cream.



Important safety information:


  • Differin Cream may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Differin Cream. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.

  • Differin Cream may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.

  • Acne may worsen in the early stages of taking Differin Cream. This is due to the action of Differin Cream on unseen lesions. The benefits of Differin Cream may be seen after 2 weeks but at least 8 weeks are needed to see consistent benefits.

  • Skin moisturizers may be used if necessary. Do not use moisturizers that contain alpha hydroxy or glycolic acids.

  • Certain cosmetic procedures, such as waxing, should not be performed on treated skin due to possible irritation.

  • Cosmetics may be used while using Differin Cream. After using cosmetics, thoroughly wash and dry the affected area before applying Differin Cream.

  • Wind and cold temperatures can also irritate the affected skin.

  • Differin Cream should be used with extreme caution in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Differin Cream while you are pregnant. It is not known if Differin Cream is found in breast milk. If you are or will be breast-feeding while you use Differin Cream, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Differin Cream:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Temporary burning and stinging; dry skin; feeling of warmth; irritation; itching; peeling; redness; scaling.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blistering; crusting; excessive redness or peeling; swelling.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch .


See also: Differin side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Differin Cream may be harmful if swallowed.


Proper storage of Differin Cream:

Store Differin Cream at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Protect from freezing. Do not store in the bathroom. Keep Differin Cream out of the reach of children and away from pets.


General information:


  • If you have any questions about Differin Cream, please talk with your doctor, pharmacist, or other health care provider.

  • Differin Cream is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Differin Cream. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Differin resources


  • Differin Side Effects (in more detail)
  • Differin Use in Pregnancy & Breastfeeding
  • Differin Drug Interactions
  • Differin Support Group
  • 14 Reviews for Differin - Add your own review/rating


Compare Differin with other medications


  • Acne

Tuesday 22 September 2009

Klinset




Klinset may be available in the countries listed below.


Ingredient matches for Klinset



Loratadine

Loratadine is reported as an ingredient of Klinset in the following countries:


  • Indonesia

International Drug Name Search

Friday 18 September 2009

Fluoresceine Minims




Fluoresceine Minims may be available in the countries listed below.


Ingredient matches for Fluoresceine Minims



Fluorescein

Fluorescein sodium (a derivative of Fluorescein) is reported as an ingredient of Fluoresceine Minims in the following countries:


  • Belgium

International Drug Name Search

Ftazidime




Ftazidime may be available in the countries listed below.


Ingredient matches for Ftazidime



Ceftazidime

Ceftazidime pentahydrate (a derivative of Ceftazidime) is reported as an ingredient of Ftazidime in the following countries:


  • Greece

International Drug Name Search

Wednesday 16 September 2009

Reg U Late




Reg U Late may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Reg U Late



Altrenogest

Altrenogest is reported as an ingredient of Reg U Late in the following countries:


  • New Zealand

International Drug Name Search

Saturday 12 September 2009

Ceftriaxon RV




Ceftriaxon RV may be available in the countries listed below.


Ingredient matches for Ceftriaxon RV



Ceftriaxone

Ceftriaxone disodium salt (a derivative of Ceftriaxone) is reported as an ingredient of Ceftriaxon RV in the following countries:


  • Bulgaria

International Drug Name Search

Monday 7 September 2009

Doxibrom




Doxibrom may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Doxibrom



Doxycycline

Doxycycline hyclate (a derivative of Doxycycline) is reported as an ingredient of Doxibrom in the following countries:


  • Portugal

International Drug Name Search

Saturday 5 September 2009

Nasalide




In the US, Nasalide is a member of the drug class nasal steroids and is used to treat Hay Fever.

Ingredient matches for Nasalide



Flunisolide

Flunisolide is reported as an ingredient of Nasalide in the following countries:


  • France

International Drug Name Search

Friday 4 September 2009

Captopril / Hydrochlorothiazide Mylan




Captopril/Hydrochlorothiazide Mylan may be available in the countries listed below.


Ingredient matches for Captopril/Hydrochlorothiazide Mylan



Captopril

Captopril is reported as an ingredient of Captopril/Hydrochlorothiazide Mylan in the following countries:


  • France

Hydrochlorothiazide

Hydrochlorothiazide is reported as an ingredient of Captopril/Hydrochlorothiazide Mylan in the following countries:


  • France

International Drug Name Search

Wednesday 2 September 2009

Blistex




In the US, Blistex (emollients topical) is a member of the drug class miscellaneous topical agents and is used to treat Herpes Simplex.

US matches:

  • Blistex Lip Balm

  • Blistex Pro Relief topical

  • Blistex topical

Ingredient matches for Blistex



Acyclovir

Aciclovir is reported as an ingredient of Blistex in the following countries:


  • Australia

International Drug Name Search

Saturday 15 August 2009

Alfuzosine Sandoz L.P.




Alfuzosine Sandoz L.P. may be available in the countries listed below.


Ingredient matches for Alfuzosine Sandoz L.P.



Alfuzosin

Alfuzosin hydrochloride (a derivative of Alfuzosin) is reported as an ingredient of Alfuzosine Sandoz L.P. in the following countries:


  • Belgium

  • France

International Drug Name Search

Friday 14 August 2009

NuvaRing


NuvaRing is a brand name of ethinyl estradiol/etonogestrel, approved by the FDA in the following formulation(s):


NUVARING (ethinyl estradiol; etonogestrel - ring; vaginal)



  • Manufacturer: ORGANON USA INC

    Approval date: October 3, 2001

    Strength(s): 0.015MG;0.12MG [RLD]

Has a generic version of NuvaRing been approved?


No. There is currently no therapeutically equivalent version of NuvaRing available.


Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of NuvaRing. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.




Related Patents


Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.




  • Drug delivery system for two or more active substances
    Patent 5,989,581
    Issued: November 23, 1999
    Inventor(s): Groenewegen; Rudolf Johannes Joseph
    Assignee(s): Akzo Nobel N.V.
    The present invention is dealing with a drug delivery system, preferably in a ring-shaped form suitable for vaginal administration, for the simultaneous release of a progestogenic steroid compound and an estrogenic steroid compound in a fixed physiological ratio over a prolonged period of time. The drug delivery system comprises at least one compartment comprising a thermoplastic polymer core containing the mixture of the progestogenic and estrogenic compounds and a thermoplastic polymer skin, the progestogenic compound being initially dissolved in the polymer core material in a relatively low degree of supersaturation.
    Patent expiration dates:

    • April 8, 2018



See also...

  • NuvaRing Consumer Information (Drugs.com)
  • NuvaRing Ring Consumer Information (Wolters Kluwer)
  • NuvaRing Consumer Information (Cerner Multum)
  • NuvaRing Advanced Consumer Information (Micromedex)
  • Etonogestrel/Ethinyl Estradiol Ring Consumer Information (Wolters Kluwer)
  • Ethinyl estradiol and etonogestrel Consumer Information (Cerner Multum)
  • Ethinyl estradiol and etonogestrel Vaginal Advanced Consumer Information (Micromedex)

Tuesday 11 August 2009

daunorubicin liposomal


Generic Name: daunorubicin liposomal (DAW noe ROO bi sin LYE poe SOE mal)

Brand Names: Daunoxome


What is daunorubicin liposomal?

Daunorubicin liposomal is a cancer (antineoplastic) medication. Daunorubicin liposomal interferes with the growth of cancer cells and slows their growth and spread in the body.


Daunorubicin liposomal is used to treat advanced HIV-associated Kaposi's sarcoma.


Daunorubicin liposomal may also be used for purposes other than those listed in this medication guide.


What is the most important information I should know about daunorubicin liposomal?


Daunorubicin liposomal should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.


Serious side effects have been reported with the use of daunorubicin liposomal including: allergic reactions (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); severe heart damage with prolonged use; decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; fever or chills; or signs of infection); severe nausea, vomiting, diarrhea, and loss of appetite; and others. Talk to your doctor about the possible side effects from treatment with daunorubicin liposomal.


Who should not use daunorubicin liposomal?


Do not use daunorubicin liposomal without first talking to your doctor if you have
  • kidney disease;

  • liver disease;


  • heart disease;




  • poor bone marrow function;




  • received radiation therapy that encompassed the heart; or




  • previously received treatment with doxorubicin (Adriamycin, Rubex), doxorubicin liposomal (Doxil), daunorubicin (Cerubidine), daunorubicin liposomal (Daunoxome), idarubicin (Idamycin), or mitoxantrone (Novantrone).



The use of daunorubicin liposomal may be dangerous if you have any of the conditions listed above.


Daunorubicin liposomal is in the FDA pregnancy category D. This means that daunorubicin liposomal is known to be harmful to an unborn baby.Do not use daunorubicin liposomal without first talking to your doctor if you are pregnant. Discuss with your doctor the appropriate use of birth control during treatment with daunorubicin liposomal if necessary. Daunorubicin liposomal passes into breast milk and may harm a nursing baby. Breast-feeding should be avoided during treatment with daunorubicin liposomal.

How should I use daunorubicin liposomal?


Daunorubicin liposomal should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.


Your doctor will determine the correct amount and frequency of treatment with daunorubicin liposomal depending upon the type of cancer being treated and other factors. Talk to your doctor if you have any questions or concerns regarding the treatment schedule.


Your doctor will probably want you to have regularly scheduled blood tests and other medical evaluations during treatment with daunorubicin liposomal to monitor progress and side effects.


Skin accidentally exposed to daunorubicin liposomal should be rinsed thoroughly with soap and warm water.


Your healthcare provider will store daunorubicin liposomal as directed by the manufacturer. If you are storing daunorubicin liposomal at home, follow the directions provided by your healthcare provider.


What happens if I miss a dose?


Contact your doctor if you miss a dose of daunorubicin liposomal.


What happens if I overdose?


If for any reason an overdose of daunorubicin liposomal is suspected, seek emergency medical attention or contact your healthcare provider immediately.

Symptoms of a daunorubicin liposomal overdose tend to be similar to side effects caused by the medication, although often more severe.


What should I avoid while using daunorubicin liposomal?


Daunorubicin liposomal can lower the activity of your immune system making you susceptible to infections. Avoid contact with people who have colds, the flu, or other contagious illnesses and do not receive vaccines that contain live strains of a virus (e.g., live oral polio vaccine) during treatment with daunorubicin liposomal. In addition, avoid contact with individuals who have recently been vaccinated with a live vaccine. There is a chance that the virus can be passed on to you.


Skin accidentally exposed to daunorubicin liposomal should be rinsed thoroughly with soap and warm water.


Daunorubicin liposomal side effects


If you experience any of the following serious side effects from daunorubicin liposomal, contact your doctor immediately:



  • an allergic reaction (including difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);




  • decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; or fever, chills, or signs of infection);




  • congestive heart failure (difficulty breathing, fluid retention, chest pain);




  • tissue or vein reactions near the site of administration;




  • liver damage (abdominal pain, yellowing of the skin or eyes);




  • nausea, vomiting, diarrhea, or loss of appetite;




  • inflamation or sores inside the mouth, throat, or intestines;




  • numbness or tingling;




  • fever, chills, or other signs of infection; or




  • back pain, flushing, and chest tightness while daunorubicin liposomal is being administered.



Other, less serious side effects may be more likely to occur. Continue taking daunorubicin liposomal and talk to your doctor if you experience:



  • temporary hair loss; or




  • red colored urine for 1 or 2 days following a dose.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Daunorubicin liposomal Dosing Information


Usual Adult Dose for Kaposi's Sarcoma:

For first line cytotoxic therapy for advanced HIV-associated Kaposi's sarcoma. (Note: Daunorubicin liposomal is not recommended for use in patients with less than advanced HIV-related Kaposi's sarcoma.

If the patient has an acceptable benefit-cardiac risk ratio and adequate blood cell counts, then the recommended dose is: 40 mg/m2 infused intravenously over 60 minutes every 2 weeks,


What other drugs will affect daunorubicin liposomal?


Do not use daunorubicin liposomal without first talking to your doctor if you have had previous treatment with doxorubicin (Adriamycin, Rubex), doxorubicin liposomal (Doxil), daunorubicin (Cerubidine), daunorubicin liposomal (Daunoxome), idarubicin (Idamycin), or mitoxantrone (Novantrone). Because there is a maximum amount of these medications that should be administered to an individual, you may not be able to use daunorubicin liposomal. Do not receive "live" vaccines during treatment with daunorubicin liposomal. Administration of a live vaccine may be dangerous during treatment with daunorubicin liposomal.

Drugs other than those listed here may also interact with daunorubicin liposomal. Talk to your doctor and pharmacist before taking any other prescription or over-the-counter medicines, including herbal products, during treatment with daunorubicin liposomal.



More daunorubicin liposomal resources


  • Daunorubicin liposomal Side Effects (in more detail)
  • Daunorubicin liposomal Use in Pregnancy & Breastfeeding
  • Daunorubicin liposomal Drug Interactions
  • Daunorubicin liposomal Support Group
  • 0 Reviews for Daunorubicin liposomal - Add your own review/rating


  • DaunoXome Prescribing Information (FDA)

  • Daunorubicin Liposomal MedFacts Consumer Leaflet (Wolters Kluwer)

  • Daunoxome Advanced Consumer (Micromedex) - Includes Dosage Information



Compare daunorubicin liposomal with other medications


  • Kaposi's Sarcoma


Where can I get more information?


  • Your healthcare provider may have additional information about daunorubicin liposomal that you may read.

See also: daunorubicin liposomal side effects (in more detail)


Friday 7 August 2009

Ciprocur




Ciprocur may be available in the countries listed below.


Ingredient matches for Ciprocur



Cyproterone

Cyproterone is reported as an ingredient of Ciprocur in the following countries:


  • Peru

International Drug Name Search

Monday 3 August 2009

Natrijev diklofenak




Natrijev diklofenak may be available in the countries listed below.


Ingredient matches for Natrijev diklofenak



Diclofenac

Diclofenac sodium salt (a derivative of Diclofenac) is reported as an ingredient of Natrijev diklofenak in the following countries:


  • Slovenia

International Drug Name Search

Sunday 26 July 2009

Cortaid




In the US, Cortaid (hydrocortisone topical) is a member of the drug class topical steroids and is used to treat Anal Itching, Aphthous Stomatitis - Recurrent, Atopic Dermatitis, Dermatitis, Eczema, Gingivitis, Proctitis, Pruritus, Psoriasis, Seborrheic Dermatitis and Skin Rash.

US matches:

  • Cortaid

  • Cortaid Intensive Therapy

  • Cortaid Maximum Strength

  • Cortaid with Aloe

Ingredient matches for Cortaid



Hydrocortisone

Hydrocortisone is reported as an ingredient of Cortaid in the following countries:


  • United States

International Drug Name Search

Rosil




Rosil may be available in the countries listed below.


Ingredient matches for Rosil



Clindamycin

Clindamycin dihydrogen phosphate (a derivative of Clindamycin) is reported as an ingredient of Rosil in the following countries:


  • Thailand

International Drug Name Search

Wednesday 22 July 2009

Gen-Combo Sterinebs




Gen-Combo Sterinebs may be available in the countries listed below.


Ingredient matches for Gen-Combo Sterinebs



Ipratropium

Ipratropium Bromide is reported as an ingredient of Gen-Combo Sterinebs in the following countries:


  • Canada

Salbutamol

Salbutamol sulfate (a derivative of Salbutamol) is reported as an ingredient of Gen-Combo Sterinebs in the following countries:


  • Canada

International Drug Name Search

Monday 13 July 2009

Calcitonin Pharmachem




Calcitonin Pharmachem may be available in the countries listed below.


Ingredient matches for Calcitonin Pharmachem



Calcitonin

Calcitonin is reported as an ingredient of Calcitonin Pharmachem in the following countries:


  • Greece

International Drug Name Search

Friday 10 July 2009

Stada Uno




Stada Uno may be available in the countries listed below.


Ingredient matches for Stada Uno



Nifedipine

Nifedipine is reported as an ingredient of Stada Uno in the following countries:


  • Singapore

International Drug Name Search

Wednesday 8 July 2009

Calciferol Oily Solution Lennon




Calciferol Oily Solution Lennon may be available in the countries listed below.


Ingredient matches for Calciferol Oily Solution Lennon



Ergocalciferol

Ergocalciferol is reported as an ingredient of Calciferol Oily Solution Lennon in the following countries:


  • South Africa

International Drug Name Search

Friday 19 June 2009

Letizen




Letizen may be available in the countries listed below.


Ingredient matches for Letizen



Cetirizine

Cetirizine is reported as an ingredient of Letizen in the following countries:


  • Bosnia & Herzegowina

  • Georgia

  • Latvia

  • Lithuania

  • Romania

  • Serbia

  • Slovenia

Cetirizine dihydrochloride (a derivative of Cetirizine) is reported as an ingredient of Letizen in the following countries:


  • Bulgaria

  • Croatia (Hrvatska)

  • Czech Republic

  • Poland

  • Slovakia

  • Slovenia

International Drug Name Search

Wednesday 17 June 2009

Valproate Sodium




Ingredient matches for Valproate Sodium



Valproic Acid

Valproate Sodium (USAN) is known as Valproic Acid in the US.

International Drug Name Search

Glossary

USANUnited States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Tuesday 9 June 2009

Digitaline Nativelle



Generic Name: digoxin (Oral route)

di-JOX-in

Commonly used brand name(s)

In the U.S.


  • Digitek

  • Lanoxicaps

  • Lanoxin

  • Lanoxin Pediatric

In Canada


  • Digitaline Nativelle

Available Dosage Forms:


  • Tablet

  • Capsule, Liquid Filled

  • Solution

  • Elixir

Therapeutic Class: Cardiovascular Agent


Pharmacologic Class: Cardiac Glycoside


Chemical Class: Digitalis Glycoside


Uses For Digitaline Nativelle


Digoxin is used in combination with a diuretic ("water pill") and an angiotensin-converting enzyme (ACE) inhibitor to treat congestive heart failure and a heart rhythm problem called atrial fibrillation.


Digoxin belongs to the class of medicines called digitalis glycosides. It is used to improve the strength and efficiency of the heart, or to control the rate and rhythm of the heartbeat. This leads to better blood circulation and reduced swelling of the hands and ankles in patients with heart problems.


This medicine is available only with your doctor's prescription.


Before Using Digitaline Nativelle


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of digoxin in children. However, infants are more likely to be very sensitive to the effects of digoxin which may require an individual dose for infants receiving digoxin.


Geriatric


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of digoxin in the elderly. However, elderly patients are more likely to have age-related kidney or heart problems which may require an adjustment in the dose for patients receiving digoxin.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Alprazolam

  • Amiodarone

  • Bemetizide

  • Bendroflumethiazide

  • Benzthiazide

  • Boceprevir

  • Buthiazide

  • Calcium

  • Chan Su

  • Chlorothiazide

  • Chlorthalidone

  • Clarithromycin

  • Clopamide

  • Conivaptan

  • Cyclopenthiazide

  • Cyclothiazide

  • Demeclocycline

  • Diphenoxylate

  • Doxycycline

  • Dronedarone

  • Erythromycin

  • Ezogabine

  • Hydrochlorothiazide

  • Hydroflumethiazide

  • Indapamide

  • Indomethacin

  • Itraconazole

  • Kyushin

  • Lapatinib

  • Lily of the Valley

  • Methyclothiazide

  • Metolazone

  • Minocycline

  • Oleander

  • Oxytetracycline

  • Pheasant's Eye

  • Polythiazide

  • Propafenone

  • Propantheline

  • Quercetin

  • Quinethazone

  • Quinidine

  • Ritonavir

  • Saquinavir

  • Spironolactone

  • Squill

  • St John's Wort

  • Succinylcholine

  • Telaprevir

  • Tetracycline

  • Trichlormethiazide

  • Verapamil

  • Xipamide

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Acarbose

  • Acebutolol

  • Alprenolol

  • Aluminum Carbonate, Basic

  • Aluminum Hydroxide

  • Aluminum Phosphate

  • Aminosalicylic Acid

  • Arbutamine

  • Atenolol

  • Atorvastatin

  • Azithromycin

  • Azosemide

  • Bepridil

  • Betaxolol

  • Bevantolol

  • Bisoprolol

  • Bucindolol

  • Canrenoate

  • Carteolol

  • Carvedilol

  • Cascara Sagrada

  • Celiprolol

  • Cholestyramine

  • Colchicine

  • Colestipol

  • Cyclosporine

  • Darunavir

  • Dihydroxyaluminum Aminoacetate

  • Dihydroxyaluminum Sodium Carbonate

  • Dilevalol

  • Diltiazem

  • Disopyramide

  • Epoprostenol

  • Esmolol

  • Etravirine

  • Flecainide

  • Fluoxetine

  • Furosemide

  • Gatifloxacin

  • Hydroxychloroquine

  • Indecainide

  • Labetalol

  • Lenalidomide

  • Lornoxicam

  • Lurasidone

  • Magaldrate

  • Magnesium Carbonate

  • Magnesium Hydroxide

  • Magnesium Oxide

  • Magnesium Trisilicate

  • Mepindolol

  • Metipranolol

  • Metoclopramide

  • Metoprolol

  • Mibefradil

  • Nadolol

  • Nebivolol

  • Nefazodone

  • Neomycin

  • Nilvadipine

  • Nisoldipine

  • Nitrendipine

  • Omeprazole

  • Oxprenolol

  • Pancuronium

  • Paromomycin

  • Penbutolol

  • Pindolol

  • Piretanide

  • Posaconazole

  • Propranolol

  • Quinine

  • Rabeprazole

  • Ranolazine

  • Rifampin

  • Rifapentine

  • Roxithromycin

  • Simvastatin

  • Sotalol

  • Sucralfate

  • Sulfasalazine

  • Talinolol

  • Telithromycin

  • Telmisartan

  • Tertatolol

  • Ticagrelor

  • Timolol

  • Torsemide

  • Tramadol

  • Trazodone

  • Trimethoprim

  • Valspodar

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Blood vessel disease (e.g., arteriovenous shunt) or

  • Hypocalcemia (low calcium in the blood) or

  • Hypoxia (low oxygen in the blood) or

  • Thyroid disease—Use with caution. Patients with these conditions may be less sensitive or resistant to the effects of digoxin.

  • Electrical cardioversion (a medical procedure)—Dose of digoxin may be reduced 1 to 2 days prior to electrical cardioversion of atrial fibrillation to avoid worsening of the condition.

  • Heart disease (e.g., amyloid heart disease, AV block, constrictive pericarditis, cor pulmonale, heart attack, hypertrophic cardiomyopathy, restrictive cardiomyopathy, sick sinus syndrome, Wolff-parkinson-white syndrome) or

  • Hypercalcemia (high calcium in the blood) or

  • Hypokalemia (low potassium in the blood) or

  • Hypomagnesemia (low magnesium in the blood)—Use with caution. May make these conditions worse.

  • Kidney disease—Use with caution. The effects may be increased because of slower removal from the body.

  • Ventricular fibrillation (heart rhythm problem)—Should not be used in patients with this condition.

Proper Use of digoxin

This section provides information on the proper use of a number of products that contain digoxin. It may not be specific to Digitaline Nativelle. Please read with care.


To keep your heart working properly, take this medicine exactly as directed even though you may feel well. Do not take more of it than your doctor ordered and do not miss any doses. Take the medicine at the same time each day. This medicine works best when there is a constant amount in the blood.


When you are taking this medicine, it is very important that you get the exact amount of medicine that you need. The dose of digoxin will be different for different patients. Your doctor will determine the proper dose of digoxin for you. Follow your doctor's orders or the directions on the label.


Measure the oral solution correctly using the marked measuring dropper or Patients cups™ that comes with the package. Rinse the dosing dropper or cup with water after each use.


Your doctor may want you to check your pulse before you take each dose of this medicine. A nurse or other caregiver can teach you how to check your pulse. Your doctor will tell you how fast your pulse should be (for adults, the usual range is 60 to 100 heartbeats per minute). If your pulse is too high or too low, call your doctor before you take the medicine.


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For heart failure or atrial fibrillation:
    • For oral dosage form (solution):
      • Adults—Dose is based on age, body weight, and medical condition and must be determined by your doctor. Your doctor may increase your dose as needed. However, the dose is usually 3 microgram per kilogram per day (mcg/kg/day).

      • Teenagers and children above 2 years of age—Dose is based on age, body weight, and medical condition and must be determined by your doctor. Your doctor may increase your dose as needed. However, the dose is usually 10 microgram per kilogram per day (mcg/kg/day).

      • Children below 2 years of age—Use and dose must be determined by your doctor.


    • For oral dosage form (tablets):
      • Adults—Your doctor will give your first few doses intravenously (rapid digitalization) and then, you'll be switched to oral tablets for maintenance therapy. A maintenance dose of 0.125 to 0.5 milligram (mg) once a day will be given depending on your body weight and medical condition.

      • Teenagers and children above 10 years of age—Dose is based on body weight and must be determined by your doctor.

      • Children below 10 years of age—Use and dose must be determined by your doctor.



Missed Dose


If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


If you miss a dose of this medicine, and you remember it within 12 hours, take it as soon as you remember. However, if you do not remember until later, skip the missed dose and go back to your regular dosing schedule. If you have any questions about this or if you miss doses for 2 or more days in a row, check with your doctor.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions While Using Digitaline Nativelle


It is very important that your doctor check your progress closely while you are using this medicine to see if it is working properly and to allow for a change in the dose. Blood tests may be needed to check for any unwanted effects.


Do not stop taking this medicine without first checking with your doctor. Stopping suddenly may cause a serious change in heart function.


Watch for signs and symptoms of overdose while you are taking this medicine. Follow your doctor's directions carefully. The amount of this medicine needed to help most people is very close to the amount that could cause serious problems from overdose. Some early warning signs of overdose are loss of appetite, nausea, vomiting, diarrhea, or problems in seeing. Other signs of overdose are changes in the rate or rhythm of the heartbeat (becoming irregular or slow), palpitations (feeling of pounding in the chest), or fainting. In infants and small children, the earliest signs of overdose are changes in the rate and rhythm of the heartbeat. Children may not show the other symptoms as soon as adults.


Your doctor may want you to carry a medical identification card or bracelet stating that you are receiving this medicine.


Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.


Before having any tests, tell your doctor that you are using this medicine. This medicine may affect the results of certain medical tests.


Digitaline Nativelle Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


More common
  • Dizziness

  • fainting

  • fast, pounding, or irregular heartbeat or pulse

  • slow heartbeat

Rare
  • Black, tarry stools

  • bleeding gums

  • blood in the urine or stools

  • bloody vomit

  • pinpoint red spots on the skin

  • rash with flat lesions or small raised lesions on the skin

  • severe stomach pain

  • unusual bleeding or bruising

Incidence not known
  • Chest pain or discomfort

  • nausea

  • shortness of breath

  • sweating

  • swelling of the feet and lower legs

  • troubled breathing

  • unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


Less common
  • Agitation or combativeness

  • anxiety

  • confusion

  • depression

  • diarrhea

  • expressed fear of impending death

  • hallucinations

  • rash

  • vomiting

Rare
  • Abdominal or stomach pain

Incidence not known
  • Blurred or loss of vision

  • disturbed color perception

  • double vision

  • halos around lights

  • headache

  • lack of feeling or emotion

  • loss of appetite

  • night blindness

  • overbright appearance of lights

  • swelling of the breasts or breast soreness in both females and males

  • tunnel vision

  • uncaring

  • weakness

  • weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More Digitaline Nativelle resources


  • Digitaline Nativelle Use in Pregnancy & Breastfeeding
  • Drug Images
  • Digitaline Nativelle Drug Interactions
  • Digitaline Nativelle Support Group
  • 6 Reviews for Digitaline Nativelle - Add your own review/rating


Compare Digitaline Nativelle with other medications


  • Atrial Fibrillation
  • Heart Failure

Saturday 6 June 2009

Stalevo 200


See also: Generic Stalevo 100, Generic Stalevo 125, Generic Stalevo 150, Generic Stalevo 50, Generic Stalevo 75


Stalevo 200 is a brand name of carbidopa/entacapone/levodopa, approved by the FDA in the following formulation(s):


STALEVO 200 (carbidopa; entacapone; levodopa - tablet; oral)



  • Manufacturer: ORION

    Approval date: August 2, 2007

    Strength(s): 50MG;200MG;200MG [RLD]

Has a generic version of Stalevo 200 been approved?


No. There is currently no therapeutically equivalent version of Stalevo 200 available.


Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Stalevo 200. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.




Related Patents


Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.




  • Pharmacologically active catechol derivatives
    Patent 5,446,194
    Issued: August 29, 1995
    Inventor(s): Backstrom; Reijo J. & Heinola; Kalevi E. & Honkanen; Erkki J. & Kaakkola; Seppo K. & Kairisalo; Pekka J. & Linden; Inge-Britt Y. & Mannisto; Pekka I. & Nissinen; Erkki A. O. & Pohto; Pentti & Pippuri; Aino K. & Pystynen; Jarmo J.
    Assignee(s): Orion-yhtyma Oy
    A compound according to formula 1 ##STR1## wherein R.sub.1 and R.sub.2 independently represent hydrogen, carbamoyl which is substituted by an alkyl of 1 to 4 carbon atoms, alkylcarbonyl of 2 to 5 carbon atoms or phenyl carbonyl, X represents halogen nitro or cyano and R.sub.3 represents ##STR2## wherein R.sub.4 represents cyano or alkylcarbonyl of 2 to 5 carbon atoms and R.sub.5 represents carbamoyl which is unsubstituted or substituted with alkyl of 1 to 8 carbon atoms or which is substituted with hydroxyalkyl of 1 to 8 carbon atoms or pharmaceutically acceptable esters and salts thereof, and a pharmaceutically acceptable carrier therefor, as well as pharmaceutical compositions containing said compounds as COMT inhibitors.
    Patent expiration dates:

    • October 19, 2013
      ✓ 
      Drug substance




  • Pharmaceutical composition comprising entacapone, levodopa, and carbidopa
    Patent 6,500,867
    Issued: December 31, 2002
    Inventor(s): Matti; Virkki & Kari; Vahervuo & Marja; Ritala & Marja; Partanen & Mervi; Niskanen & Jarmo; Lintulaakso & Marja; Laaksonen & Lasse; Kervinen & Sari; Kallioinen
    Assignee(s): Orion Corporation
    An oral solid fixed dose composition comprising pharmacologically effective amounts of entacapone, levodopa, and carbidopa, or pharmaceutically acceptable salts or hydrates thereof, and comprising at least one pharmaceutically acceptable excipient. The composition can be used, e.g., for the treatment of Parkinson's disease.
    Patent expiration dates:

    • June 29, 2020
      ✓ 
      Patent use: TREATMENT OF PARKINSON'S DISEASE
      ✓ 
      Drug product




  • Pharmaceutical composition comprising entracapone, levodopa, and carbidopa
    Patent 6,797,732
    Issued: September 28, 2004
    Inventor(s): Matti; Virkki & Kari; Vahervuo & Marja; Ritala & Marja; Partanen & Mervi; Niskanen & Jarmo; Lintulaakso & Marja; Laaksonen & Lasse; Kervinen & Sari; Kallioinen
    Assignee(s): Orion Corporation
    An oral solid fixed dose composition comprising pharmacologically effective amounts of entacapone, levodopa, and carbidopa, or pharmaceutically acceptable salts or hydrates thereof, and comprising at least one pharmaceutically acceptable excipient. The composition can be used, e.g., for the treatment of Parkinson's disease.
    Patent expiration dates:

    • June 29, 2020
      ✓ 
      Drug product



See also...

  • Stalevo 200 Consumer Information (Cerner Multum)
  • Carbidopa/Entacapone/Levodopa Consumer Information (Wolters Kluwer)
  • Carbidopa/Levodopa/Entacapone Consumer Information (Wolters Kluwer)
  • Carbidopa, entacapone, and levodopa Consumer Information (Cerner Multum)
  • Carbidopa, entacapone, and levodopa Advanced Consumer Information (Micromedex)

Thursday 4 June 2009

bismuth subsalicylate


BIZ-muth sub-sa-LIS-i-late


Commonly used brand name(s)

In the U.S.


  • Bismatrol

  • Diotame

  • Kaopectate

  • Kapectolin

  • Kola-Pectin

  • Pepto Bismol

In Canada


  • Bismuth Extra Strength

  • Bismuth Original Formula

  • Pepto-Bismol

  • Stomach Relief - Regular Formula

Available Dosage Forms:


  • Suspension

  • Tablet, Chewable

  • Tablet

Therapeutic Class: Antacid, Bismuth Containing


Chemical Class: Salicylate, Non-Aspirin


Uses For bismuth subsalicylate


Bismuth subsalicylate is used to treat diarrhea in adults and teenagers. It is also used to relieve the symptoms of an upset stomach, such as heartburn, indigestion, and nausea in adults and teenagers.


bismuth subsalicylate is available without a prescription.


Before Using bismuth subsalicylate


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For bismuth subsalicylate, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to bismuth subsalicylate or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


bismuth subsalicylate should not be used in children younger than 12 years of age. The fluid loss caused by diarrhea may result in a severe condition. In older children with diarrhea, medicine for diarrhea may be used, but it is also very important that a sufficient amount of liquids be given to replace the fluid lost by the body. If you have any questions about this, check with your health care professional.


Also, children are usually more sensitive to the effects of salicylates, especially if they have a fever or have lost large amounts of body fluid because of vomiting, diarrhea, or sweating.


The bismuth in bismuth subsalicylate may cause severe constipation in children.


In addition, do not use bismuth subsalicylate to treat nausea or vomiting in children or teenagers who have or are recovering from the flu or chickenpox. If nausea or vomiting is present, check with the child's doctor immediately because this could be an early sign of Reye's syndrome.


Geriatric


The fluid loss caused by diarrhea may result in a severe condition. For this reason, elderly persons with diarrhea should not take bismuth subsalicylate without first checking with their doctor. It is also very important that a sufficient amount of liquids be taken to replace the fluid lost by the body. If you have any questions about this, check with your health care professional.


Also, the elderly may be more sensitive to the effects of salicylates. This may increase the chance of side effects during treatment. In addition, the bismuth in bismuth subsalicylate may cause severe constipation in the elderly.


Breast Feeding


Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using bismuth subsalicylate.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking bismuth subsalicylate, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using bismuth subsalicylate with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Methotrexate

Using bismuth subsalicylate with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Doxycycline

  • Probenecid

  • Sulfinpyrazone

  • Tamarind

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of bismuth subsalicylate. Make sure you tell your doctor if you have any other medical problems, especially:


  • Dysentery—This condition may get worse; a different kind of treatment may be needed

  • Gout—The salicylate in bismuth subsalicylate may worsen the gout and make the medicines taken for gout less effective

  • Hemophilia or other bleeding problems—The salicylate in bismuth subsalicylate may increase the chance of bleeding

  • Kidney disease—There is a greater chance of side effects because the body may be unable to get rid of the bismuth subsalicylate

  • Stomach ulcer—Use of bismuth subsalicylate may make the ulcer worse

Proper Use of bismuth subsalicylate


Make certain your health care professional knows if you are on any special diet, such as a low-sodium or low-sugar diet.


For safe and effective use of bismuth subsalicylate:


  • Follow your doctor's instructions if bismuth subsalicylate was prescribed.

  • Follow the manufacturer's package directions if you are treating yourself.

For patients using bismuth subsalicylate to treat diarrhea:


  • It is very important that the fluid lost by the body be replaced and that a proper diet be followed. For the first 24 hours you should drink plenty of clear liquids, such as ginger ale, decaffeinated cola, decaffeinated tea, broth, and gelatin. During the next 24 hours you may eat bland foods, such as cooked cereals, bread, crackers, and applesauce. Fruits, vegetables, fried or spicy foods, bran, candy, and caffeine and alcoholic beverages may make the diarrhea worse.

  • If too much fluid has been lost by the body due to the diarrhea a serious condition may develop. Check with your doctor as soon as possible if any of the following signs of too much fluid loss occur:
    • Decreased urination

    • Dizziness and lightheadedness

    • Dryness of mouth

    • Increased thirst

    • Wrinkled skin


If you are taking the oral suspension: Use the dose cup that is included to measure out the right amount of medicine. If you are unsure, contact your doctor or pharmacist.


If you are taking the oral tablets: Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.


If you are taking the chewable tablets: Chew up the tablet or allow it to completely disintegrate in your mouth before swallowing it.


Dosing


The dose of bismuth subsalicylate will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of bismuth subsalicylate. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For oral dosage form (suspension):
    • For diarrhea or upset stomach:
      • Adults and teenagers—The usual dose is 2 tablespoonfuls every half-hour to one hour if needed. You should not take more than 16 tablespoonfuls of the regular-strength suspension or 8 tablespoonfuls of the concentrate in twenty-four hours.

      • Children—Should not be used in children younger than 12 years of age.



  • For oral dosage forms (tablets or chewable tablets):
    • For diarrhea or upset stomach:
      • Adults and teenagers—The usual dose is 2 tablets every half-hour to one hour. You should not take more than 16 tablets in twenty-four hours.

      • Children—Should not be used in children younger than 12 years of age.



Missed Dose


If you miss a dose of bismuth subsalicylate, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Precautions While Using bismuth subsalicylate


Check the labels of all over-the-counter (OTC), nonprescription, and prescription medicines you now take. If any contain aspirin or other salicylates, be especially careful. Using other salicylate-containing products while taking bismuth subsalicylate may lead to overdose. If you have any questions about this, check with your health care professional.


For diabetic patients:


  • False urine sugar test results may occur if you are regularly taking large amounts of bismuth subsalicylate or other salicylates.

  • Smaller doses or occasional use of bismuth subsalicylate usually will not affect urine sugar tests. However, check with your health care professional (especially if your diabetes is not well-controlled) if:
    • you are not sure how much salicylate you are taking every day.

    • you notice any change in your urine sugar test results.

    • you have any other questions about this possible problem.


If you think that you or anyone else may have taken an overdose, get emergency help at once. Taking an overdose of bismuth subsalicylate may cause unconsciousness or death. Signs of overdose include convulsions (seizures), hearing loss, confusion, ringing or buzzing in the ears, severe drowsiness or tiredness, severe excitement or nervousness, and fast or deep breathing.


If you are taking bismuth subsalicylate for diarrhea, check with your doctor:


  • if your symptoms do not improve within 2 days or if they become worse.

  • if you also have a high fever.

bismuth subsalicylate Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


In some patients bismuth subsalicylate may cause dark tongue and/or grayish black stools. This is only temporary and will go away when you stop taking bismuth subsalicylate.


  • Anxiety

  • any loss of hearing

  • confusion

  • constipation (severe)

  • diarrhea (severe or continuing)

  • difficulty in speaking or slurred speech

  • dizziness or lightheadedness

  • drowsiness (severe)

  • fast or deep breathing

  • headache (severe or continuing)

  • increased sweating

  • increased thirst

  • mental depression

  • muscle spasms (especially of face, neck, and back)

  • muscle weakness

  • nausea or vomiting (severe or continuing)

  • ringing or buzzing in ears (continuing)

  • stomach pain (severe or continuing)

  • trembling

  • uncontrollable flapping movements of the hands (especially in elderly patients) or other uncontrolled body movements

  • vision problems

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: bismuth subsalicylate side effects (in more detail)



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