Friday 26 March 2010

Sulbutiamine




Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

A11DA02

CAS registry number (Chemical Abstracts Service)

0003286-46-2

Chemical Formula

C32-H46-N8-O6-S2

Molecular Weight

702

Therapeutic Category

Vitamin B₁

Chemical Name

Propanoic acid, 2-methyl-, dithiobis[3-[1-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino] ethylidene]-3,1-propanediyl] ester

Foreign Names

  • Sulbutiaminum (Latin)
  • Sulbutiamin (German)
  • Sulbutiamine (French)
  • Sulbutiamina (Spanish)

Generic Names

  • Bisibutiamine (OS: JAN)
  • Sulbutiamine (OS: DCF)
  • Bisibutiamin (IS)
  • S 5007 (IS)

Brand Names

  • Acralion
    Servier, Netherlands Antilles; Servier, Aruba; Servier, Barbados; Servier, Bermuda; Servier, Bahamas; Servier, Grenada; Servier, Guyana; Servier, Jamaica; Servier, Cayman Islands; Servier, Saint Lucia; Servier, Trinidad & Tobago; Servier, Saint Vincent & The Grenadines


  • Arcalion
    Euroetika, Colombia; Grünenthal, Chile; Grünenthal, Peru; Serdia, India; Servier, United Arab Emirates; Servier, Bahrain; Servier, Brazil; Servier, Switzerland; Servier, Costa Rica; Servier, Dominican Republic; Servier, Egypt; Servier, Spain; Servier, France; Servier, Ghana; Servier, Guatemala; Servier, Guyana; Servier, Hong Kong; Servier, Honduras; Servier, Iraq; Servier, Jordan; Servier, Kuwait; Servier, Lebanon; Servier, Luxembourg; Servier, Malta; Servier, Mexico; Servier, Malaysia; Servier, Nigeria; Servier, Nicaragua; Servier, Oman; Servier, Panama; Servier, Philippines; Servier, Portugal; Servier, Qatar; Servier, Saudi Arabia; Servier, Sudan; Servier, Singapore; Servier, El Salvador; Servier, Syria; Servier, Thailand; Servier, Turkey; Servier, Venezuela; Servier, Vietnam; Servier, Yemen


  • Arcatamin
    Danapha, Vietnam


  • Arnion
    HG.Pharm, Vietnam


  • Enerion
    Egis, Russian Federation; Servier, Romania


  • Megastene
    Servier, Argentina


  • Pymeacolion
    PMP, Vietnam


  • Surmenalit
    Faes, Costa Rica; Faes, Dominican Republic; Faes, Spain; Faes, Guatemala; Faes, Honduras; Faes, Nicaragua; Faes, Panama; Faes, El Salvador

International Drug Name Search

Glossary

DCFDénomination Commune Française
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Saturday 20 March 2010

Indomethacin Vida




Indomethacin Vida may be available in the countries listed below.


Ingredient matches for Indomethacin Vida



Indometacin

Indometacin is reported as an ingredient of Indomethacin Vida in the following countries:


  • Hong Kong

International Drug Name Search

Thursday 18 March 2010

Oxybutynin System



Pronunciation: OX-i-BUE-ti-nin
Generic Name: Oxybutynin
Brand Name: Oxytrol


Oxybutynin System is used for:

Relieving symptoms of bladder problems (urinary urgency, frequency, or leakage; loss of bladder control; and painful urination) in certain patients. It may also be used for other conditions as determined by your doctor.


Oxybutynin System is an anticholinergic. It works by relaxing muscles in the bladder.


Do NOT use Oxybutynin System if:


  • you are allergic to any ingredient in Oxybutynin System

  • you have bladder blockage or are unable to urinate

  • you have certain stomach or bowel problems (eg, blockage, decreased muscle movement)

  • you have uncontrolled narrow-angle glaucoma

  • you are taking a solid oral potassium product (eg, tablet)

Contact your doctor or health care provider right away if any of these apply to you.



Before using Oxybutynin System:


Some medical conditions may interact with Oxybutynin System. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have trouble urinating or have very poor health

  • if you have a history of heart problems (eg, heart failure, fast or irregular heartbeat), high blood pressure, nervous system problems, liver or kidney problems, myasthenia gravis, an enlarged prostate, an overactive thyroid, esophagus problems (eg, reflux disease, inflammation, narrowing), stomach or bowel problems (eg, colitis, inflammation, constipation), or a hiatal hernia

  • if you have a history of glaucoma or increased pressure in the eyes, or if you are at risk of glaucoma (eg, family history of glaucoma)

Some MEDICINES MAY INTERACT with Oxybutynin System. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Bisphosphonates (eg, alendronate) because the risk of irritation of the esophagus may be increased

  • Other anticholinergic medicines (eg, scopolamine), azole antifungals (eg, ketoconazole), or macrolide antibiotics (eg, erythromycin) because they may increase the risk of Oxybutynin System's side effects

  • Solid oral potassium products (eg, tablets) because the risk of stomach or bowel irritation may be increased by Oxybutynin System

  • Phenothiazines (eg, chlorpromazine) because their effectiveness may be decreased by Oxybutynin System and they may increase the risk of Oxybutynin System's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Oxybutynin System may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Oxybutynin System:


Use Oxybutynin System as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • An extra patient leaflet is available with Oxybutynin System. Talk to your pharmacist if you have questions about this information.

  • Apply the patch to a clean, dry, smooth area of your skin on your stomach, hips, or buttocks. Apply it to an area under clothing to protect it from sunlight. Avoid applying it to your waistline because clothing may rub against the patch.

  • Do NOT apply the patch to oily, damaged, or irritated skin. Avoid using oils, lotions, or powders near the application site because the patch may not stick to your skin.

  • To use Oxybutynin System, open the pouch and remove the patch. Apply it right away. Carefully remove the first protective liner and place the patch firmly onto your skin. Do not touch the adhesive side of the patch. Bend the patch in half and gently roll the remaining part onto your skin. The second protective liner should come off of the patch. Gently apply firm pressure over the patch to be sure it stays in place.

  • When it is time to apply a new patch, remove the old patch carefully. Fold the patch in half with the sticky sides together. Discard the patch out of the reach of children and pets because it may still contain medicine.

  • Use a different skin site each time you apply a new patch. Do not reuse the same site within 7 days.

  • Use Oxybutynin System on a regular schedule to get the most benefit from it. Using Oxybutynin System at the same time each day will help you remember to use it.

  • Continue to use Oxybutynin System even if you feel well. Do not miss any doses.

  • If the patch comes off, press it back in place and continue to follow your regular application schedule. If it does not stay on, throw it away and put a new patch on in a different area. Continue to follow your regular application schedule.

  • If you forget to change the patch on the correct day, remove the old patch and apply a new patch to a different application site as soon as you remember. Continue to follow your regular application schedule. Do not use 2 patches at once.

Ask your health care provider any questions you may have about how to use Oxybutynin System.



Important safety information:


  • Oxybutynin System may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Oxybutynin System with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Check with your doctor before you drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Oxybutynin System; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.

  • Oxybutynin System may cause decreased sweating. Do not become overheated in hot weather or while you are being active; heatstroke may occur. Contact your doctor if you have been exposed to high temperatures and you develop fever; flushing; hot, dry skin; severe or persistent headache; dizziness; sudden fatigue; fast heartbeat; seizures; or fainting.

  • Oxybutynin System may cause dry mouth. To help relieve dry mouth, suck on sugarless hard candy or ice chips, chew sugarless gum, drink water, or use a saliva substitute. Ask your doctor or pharmacist if you have any questions.

  • A serious side effect called angioedema has been reported with the use of oral dosage forms of Oxybutynin System (eg, tablets). Contact your doctor at once if you develop swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness.

  • Using Oxybutynin System while bathing, swimming, showering, or exercising will not change the way it works. However, avoid rubbing the patch area during these activities.

  • Always remove the patch carefully and slowly to avoid damage to your skin. If there is adhesive left on your skin, gently wash the area with warm, soapy water. You may also use baby oil or a medical adhesive removal pad if needed. Do not use alcohol or nail polish remover because these may irritate the skin.

  • After removing the patch, there may be minor redness of your skin. It should disappear after several hours. Tell your doctor if the irritation or redness becomes worse or if it does not go away.

  • Use Oxybutynin System with caution in the ELDERLY; they may be more sensitive to its effects.

  • Oxybutynin System should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: It is not known if Oxybutynin System can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Oxybutynin System while you are pregnant. It is not known if Oxybutynin System is found in breast milk. If you are or will be breast-feeding while you use Oxybutynin System, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Oxybutynin System:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Blurred vision; constipation; diarrhea; dizziness; drowsiness; dry eyes, nose, skin, or mouth; headache; indigestion; nausea; minor redness, itching, or irritation at patch application site; stomach pain.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty swallowing or breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness); confusion; difficult or painful urination; fast or irregular heartbeat; fever; hallucinations; mental or mood changes (eg, agitation); pain, burning, blistering, or oozing at the application site; seizures; swelling of the hands, ankles, or feet; vision problems.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Oxybutynin side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include coma; delirium; fever; flushing; hallucinations; inability to urinate; irregular heartbeat; paralysis; seizures; severe or persistent dizziness or headache; tremor; trouble breathing; vomiting.


Proper storage of Oxybutynin System:

Store Oxybutynin System at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store in original packaging until just before use. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Oxybutynin System out of the reach of children and away from pets.


General information:


  • If you have any questions about Oxybutynin System, please talk with your doctor, pharmacist, or other health care provider.

  • Oxybutynin System is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Oxybutynin System. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Oxybutynin resources


  • Oxybutynin Side Effects (in more detail)
  • Oxybutynin Use in Pregnancy & Breastfeeding
  • Drug Images
  • Oxybutynin Drug Interactions
  • Oxybutynin Support Group
  • 40 Reviews for Oxybutynin - Add your own review/rating


Compare Oxybutynin with other medications


  • Dysuria
  • Hyperhidrosis
  • Overactive Bladder
  • Prostatitis
  • Urinary Incontinence

Sunday 14 March 2010

Isoptine




Isoptine may be available in the countries listed below.


Ingredient matches for Isoptine



Verapamil

Verapamil is reported as an ingredient of Isoptine in the following countries:


  • Tunisia

Verapamil hydrochloride (a derivative of Verapamil) is reported as an ingredient of Isoptine in the following countries:


  • Belgium

  • France

International Drug Name Search

Saturday 13 March 2010

Adenosina Biol




Adenosina Biol may be available in the countries listed below.


Ingredient matches for Adenosina Biol



Adenosine

Adenosine is reported as an ingredient of Adenosina Biol in the following countries:


  • Argentina

International Drug Name Search

Micanol




In the US, Micanol is a member of the drug class topical antipsoriatics and is used to treat Psoriasis.

Ingredient matches for Micanol



Dithranol

Dithranol is reported as an ingredient of Micanol in the following countries:


  • Australia

  • Austria

  • Bangladesh

  • Germany

  • Israel

  • New Zealand

  • Portugal

  • United Kingdom

International Drug Name Search

Thursday 11 March 2010

Mukolen




Mukolen may be available in the countries listed below.


Ingredient matches for Mukolen



Eprazinone

Eprazinone dihydrochloride (a derivative of Eprazinone) is reported as an ingredient of Mukolen in the following countries:


  • Bosnia & Herzegowina

  • Croatia (Hrvatska)

  • Slovenia

International Drug Name Search

Friday 5 March 2010

Glucotab




Glucotab may be available in the countries listed below.


Ingredient matches for Glucotab



Glibenclamide

Glibenclamide is reported as an ingredient of Glucotab in the following countries:


  • Bangladesh

International Drug Name Search

Thursday 4 March 2010

Sulfametizol Actavis




Sulfametizol Actavis may be available in the countries listed below.


Ingredient matches for Sulfametizol Actavis



Sulfamethizole

Sulfamethizole is reported as an ingredient of Sulfametizol Actavis in the following countries:


  • Denmark

Sulfamethizole sodium salt (a derivative of Sulfamethizole) is reported as an ingredient of Sulfametizol Actavis in the following countries:


  • Denmark

International Drug Name Search

Wednesday 3 March 2010

Lamotrigine Hexal




Lamotrigine Hexal may be available in the countries listed below.


Ingredient matches for Lamotrigine Hexal



Lamotrigine

Lamotrigine is reported as an ingredient of Lamotrigine Hexal in the following countries:


  • Hungary

International Drug Name Search

Tuesday 2 March 2010

CO Etidrocal




CO Etidrocal may be available in the countries listed below.


Ingredient matches for CO Etidrocal



Calcium Carbonate

Calcium Carbonate is reported as an ingredient of CO Etidrocal in the following countries:


  • Canada

Etidronic Acid

Etidronic Acid disodium salt (a derivative of Etidronic Acid) is reported as an ingredient of CO Etidrocal in the following countries:


  • Canada

International Drug Name Search