Saturday 28 July 2012

Tobrex Drops


Pronunciation: toe-bra-MYE-sin
Generic Name: Tobramycin
Brand Name: Examples include AK-Tob and Tobrex


Tobrex Drops are used for:

Treating eye infections.


Tobrex Drops are an antibiotic. It works by killing or slowing the growth of certain types of bacteria.


Do NOT use Tobrex Drops if:


  • you are allergic to any ingredient in Tobrex Drops or to similar medicines

Contact your doctor or health care provider right away if any of these apply to you.



Before using Tobrex Drops:


Some medical conditions may interact with Tobrex Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Tobrex Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Cephalosporins by injection (eg, ceftazidime) because they may decrease Tobrex Drops's effectiveness

  • Cyclosporine, fludarabine, loop diuretics (eg, furosemide), methoxyflurane, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, indomethacin), nitrosoureas (eg, streptozocin), polypeptide antibiotics (eg, polymyxin B), or vancomycin injection because they may increase the risk of Tobrex Drops's side effects, including increased risk of kidney or hearing problems

  • Cephalosporins by injection (eg, ceftazidime), nondepolarizing muscle relaxants (eg, pancuronium), or succinylcholine because their side effects may be increased by Tobrex Drops

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tobrex Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Tobrex Drops:


Use Tobrex Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Remove contact lenses before you use Tobrex Drops.

  • Do not wear contact lenses while you are using Tobrex Drops. Take care of your contact lenses as directed by the manufacturer. Check with your doctor before you use them.

  • To use Tobrex Drops in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.

  • To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.

  • To clear up your infection completely, take/use Tobrex Drops for the full course of treatment. Keep taking/using it even if you feel better in a few days.

  • Tobrex Drops works best if it is used at the same time each day.

  • Do not miss any doses. If you miss a dose of Tobrex Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Ask your health care provider any questions you may have about how to use Tobrex Drops.



Important safety information:


  • Tobrex Drops may cause blurred vision. Use Tobrex Drops with caution. Do not drive or perform other possibly unsafe tasks if you cannot see clearly.

  • If your symptoms do not get better within a few days or if they get worse, check with your doctor.

  • Be sure to use Tobrex Drops for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

  • Long-term or repeated use of Tobrex Drops may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.

  • Tobrex Drops should not be used in CHILDREN younger than 2 months old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tobrex Drops while you are pregnant. It is not known if Tobrex Drops are found in breast milk. Do not breast-feed while using Tobrex Drops.


Possible side effects of Tobrex Drops:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Burning or stinging in the eye.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); eye or eyelid swelling, itching, or redness.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Tobrex side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; eye pain; eye watering; swelling and itching of the eyelid.


Proper storage of Tobrex Drops:

Store Tobrex Drops at room temperature, between 46 and 80 degrees F (8 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tobrex Drops out of the reach of children and away from pets.


General information:


  • If you have any questions about Tobrex Drops, please talk with your doctor, pharmacist, or other health care provider.

  • Tobrex Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Tobrex Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Tobrex resources


  • Tobrex Side Effects (in more detail)
  • Tobrex Use in Pregnancy & Breastfeeding
  • Tobrex Support Group
  • 0 Reviews for Tobrex - Add your own review/rating


Compare Tobrex with other medications


  • Conjunctivitis, Bacterial

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